© 2016 by Anastasiia Vedernikova.

/ "EVA" MACHINE. CREATION OF ORGANS FOR TRANSPLANTATION /

The problem of organ transplantation is a pretty big issue worldwide, and not every patient is able to get a transplant. In a collaboration with "3D Bioprinting solutions"(Russia) the Project Eva was created which solves the problem of transplants deficit. Each patient will have a chance to get a transplant.
The "Eva" machine grows organs for the purpose of transplantation from stem and fat cell of the patient. A new organ can be printed and grown in several weeks. This solution will significantly decrease the black market of organ donation. People will not need to look for illegal ways to get the organ. 

Video presentation of "EVA" Machine

Strategy: Definition of the Problem & Solution

Definition of the Product and Ideation

Such a machine doesn't have any analogues. The challange was to identify each function that this machine should have, and to make them work together in an ergonomic and logical way. The visual aspect of the project played a significant role. The machine should convey the idea of new life, hope, care, and protection. That's why the name of the machine is "Eva" which means "giving birth."

Idea Development

Numerous sketches were made in order to find the most appropriate design solution. Small 3D prototypes were made out of paper and cardboard. The big prototype was made out of penoplex using sculpture technique and with the use of 3D milling machine.

Interaction Design and Creation of the Workflow

In collaboration with bio-engeneers I determined the workflow for "Eva" machine. It includes 4 main stages:

 

stage 1 : Microfluidics includes creation of cell spheroids that are formed from biomaterial that is derived from fat cells of the patient. After the formation
of spheroids, they are delivered to the 3D printing part of the machine, and are packaged into cartriges for 3D printing.

 

stage 2 is the process of Bioprinting. The machine picks the cartrige with
the required set of cells and changes them sequentially. The printing process takes place in the chamber in the top part of the machine and usually takes several hours.

 

stage 3 : at the Stage of Bioreactor, the printed organ is placed in the solution with nutrients in the bioreactor where it goes through the process of maturing.
It can take up to several weeks. At this stage the smaller part of the machine is detached from the big one, and is put aside for the ripening process. Users can observe this process through the glass window in the chamber.

 

stage 4 : the final stage is the stage of the Thermocontainer. The organ that
is ready for transplantation is placed in the thermocontainer that also has
a liquid with nutrients. The thermocontainer can be extracted from the bottom part of the machine.

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